Antimicrobials, antibiotics among them, are unique among medications in the way they intersect personal and public health. Successful treatment of patients for bacterial infections will result in decreased spread of infections in the community. Not long after the discovery of these miracle drugs, however, patients’ use of antibiotics also created resistant bacteria, which is a serious public health concern. It is estimated that more than 70% of illness-causing bacteria are resistant to at least 1 antibiotic. Numbers may lie, but with an estimated 50,000 deaths due to antibiotic resistance in 2015 in the United States and Europe alone—and a projected death toll of 10 million worldwide every year by 2050—the continued benefits from antibiotics may be dwindling rapidly. In the United States alone, every year 23,000 deaths and more than 2 million infections are attributed to antibiotic-resistant bacteria. The primary reason for the increase in antibiotic resistance is its excessive use.
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