The ADA reports that a “study by Poole et al. in the May 2016 issue of mSphere...was designed to examine whether use of consumer products,” including toothpaste, “would alter gut microbiome composition, endocrine function, and markers for obesity, diabetes, and inflammation.” The ADA says the study does not provide insight as to how fluoride toothpaste containing triclosan “[reduces] plaque and gingivitis more than toothpaste containing fluoride alone,” as was demonstrated in a 2013 Cochrane review. Moreover, the results of the mSphere study “are not consistent with the hypotheses that use of triclosan at physiologic levels achieved through the use of consumer products has a major impact on human gut or oral microbiome composition.”
Regarding the mSphere study specifically, HealthDay also reports that “triclosan doesn’t dramatically alter the microbiome of the gut or the mouth, or significantly affect the endocrine system.” After randomizing “13 healthy people to use household and personal care products with or without the ingredient,” researchers found “little effect on the endocrine system” and “now major blow to oral flora or gut flora.”
TIME reports that “in light of new evidence” that the antibacterial triclosan may be linked to “bacteria resistance, hormone disruption, and possibly even liver cancer,” the Food and Drug Administration is “currently reviewing” those studies.
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